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Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

2 Oct 2019

Abstract excerpt

Mild traumatic brain injury (mTBI) disproportionately affects military servicemembers and is very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker for mTBI cases with persistent post concussive symptoms. To examine the potential of neuronally – derived (NDE) and astrocytic-derived (ADE) exosome cargo proteins as biomarkers of chronic mTBI in younger adults, we examined...

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Identifiers

PMID: 31680797
DOI: 10.3389/fnins.2019.01005

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