Article

Leveraging neural networks to correct FoldX free energy estimates

2024-09-25

Abstract excerpt

Proteins play a pivotal role in many biological processes, and changes in their amino acid sequences can lead to dysfunction and disease. These changes can affect protein folding or interaction with other biomolecules, such as preventing antibodies from inhibiting a viral infection or causing proteins to misfold. The ability to predict the effects of mutations in proteins is crucial. Although experimental techniqu...

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Literature Corpus work: 17731b18-ffff-50ba-9dfd-f12f59adb74d
DOI: 10.1101/2024.09.23.614615

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