Article
Flowers for Algernon: steroid dysgenesis, epigenetics and brain disorders.
Pharmacological reports : PR - 1 Jan 2012
Sanders Bryan K
Abstract excerpt
While a recent study has reported that early citalopram exposure alters cortical network function and produces autistic-like behaviors in male rats, when evaluating antidepressant animal models of autism spectrum disorder (ASD) it is important to note that some selective serotonin (5-HT) reuptake inhibitors alter 3α-hydroxysteroid dehydrogenase activity, and thus steroidogenesis. At least one study has examined...
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