Article
Imperfect duplicate insertions type of mutations in plasmepsin V modulates binding properties of PEXEL motifs of export proteins in Indian Plasmodium vivax.
PloS one - 1 Jan 2013
Rawat Manmeet, Vijay Sonam, Gupta Yash, Tiwari Pramod Kumar, Sharma Arun
Abstract excerpt
INTRODUCTION: Plasmepsin V (PM-V) have functionally conserved orthologues across the Plasmodium genus who's binding and antigenic processing at the PEXEL motifs for export about 200-300 essential proteins is important for the virulence and viability of the causative Plasmodium species. This study was undertaken to determine P. vivax plasmepsin V Ind (PvPM-V-Ind) PEXEL motif export pathway for...
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