Article
Effect of Combination Treatments of Apigenin and Chemotherapy on Apoptosis- Related Genes and Proteins in Acute Leukaemia Cell Lines
2021-11-30
Abstract excerpt
Apigenin is a dietary polyphenol found abundantly in fruit and vegetables. It has been shown to sensitize acute lymphoid and myeloid leukaemia cells to topoisomerase inhibitor agents (e.g., etoposide), and alkylating agents (e.g., cyclophosphamide), reducing ATP levels and inducing apoptosis; whilst being protective to control haematopoietic stem cells. This study analysed the expression profiles of intrinsic and...
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Identifiers and source
- Literature Corpus work
- d8ae48ef-c6fd-5f6b-a72a-b595420902b8
- DOI
- 10.21203/rs.3.rs-1081612/v1