Article

Predicting the direction of phenotypic difference

2024-02-23

Abstract excerpt

Predicting phenotypes from genomic data is a key goal in genetics, but for most complex phenotypes, predictions are hampered by incomplete genotype-to-phenotype mapping. Here, we describe a more attainable approach than quantitative predictions, which is aimed at qualitatively predicting phenotypic differences. Despite incomplete genotype-to-phenotype mapping, we show that it is relatively easy to determine which...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 16ac6b5e-49b6-51be-b998-a0c18fe779a8
DOI: 10.1101/2024.02.22.581566

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting the direction of phenotypic differenceDOI 10.1101/2024.02.22.581566Read

Predicting phenotypic variation from genotypes, phenotypes and a combination of the two.Semantic proximity Read

Machine learning for predicting phenotype from genotype and environment.Semantic proximity Read

Genetic architecture of quantitative traits and complex diseases.Semantic proximity Read

Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture.Semantic proximity Read

Towards holistic phenotype prediction beyond genotypic data.Semantic proximity Read

Genotype to phenotype: lessons from model organisms for human genetics.Semantic proximity Read

Predicting quantitative traits from genome and phenome with near perfect accuracySemantic proximity Read

Genotype-phenotype mapping in a post-GWAS world.Semantic proximity Read

Predicting quantitative traits from genome and phenome with near perfect accuracy.Semantic proximity Read

Genetic variation: Giving context to phenotype prediction.Semantic proximity Read

Beyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experience.Semantic proximity Read

From the phenotype to the genotype via bioinformatics.Semantic proximity Read