Back to search

Article

Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects

2024-01-05

Abstract excerpt

Spinocerebellar ataxia type 3 (SCA3), a neurodegenerative disorder caused by a CAG expansion in the ATXN3 gene, is the most common spinocerebellar ataxia subtype worldwide. Currently, there is no therapy to stop or prevent disease progression. Promising therapeutic strategies are emerging, but their translation into clinical practice requires sensitive and reliable biomarkers. Blood circulating extracellular vesi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
16946c06-b47b-525a-9bba-5237573bb555
DOI
10.1101/2024.01.04.574044
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjectsDOI 10.1101/2024.01.04.574044
Identification of a Potential Exosomal Biomarker in Spinocerebellar Ataxia Type 3/Machado–Joseph DiseaseSemantic proximity
Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington's disease.Semantic proximity
Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington’s diseaseSemantic proximity
Small nucleolar RNAs in plasma and their discriminatory power as diagnostic biomarkers of Alzheimer’s diseaseSemantic proximity
Next-Generation RNA-Sequencing of Serum Small Extracellular Vesicles Discovers Potential Diagnostic Biomarkers for Dementia With Lewy BodiesSemantic proximity
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron diseaseSemantic proximity
Ataxin-2: From RNA Control to Human Health and DiseaseSemantic proximity
Different RNA profiles in plasma derived small and large extracellular vesicles of Neurodegenerative diseases patientsSemantic proximity
Therapeutic effects of engineered exosome-based miR-25 and miR-181a treatment in spinocerebellar ataxia type 3 mice by silencing ATXN3Semantic proximity
Blood and cerebellar abundance of <i>ATXN3</i> splice variants in spinocerebellar ataxia type 3/Machado-Joseph diseaseSemantic proximity
Extracellular Vesicles Long RNA Sequencing Reveals Abundant mRNA, circRNA, and lncRNA in Human Blood as Potential Biomarkers for Cancer DiagnosisSemantic proximity
Blood-Based Circular RNAs Enable Early and Accurate Alzheimer’s Disease DiagnosisSemantic proximity
Select a neighboring publication to make it the new centre.