Article

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.

2018-03-01

Abstract excerpt

VOLUME 293 (2018) PAGES 2408–2421 PAGE 2409: Fig. 1 featured an arrow indicating a lysine to threonine mutation at residue 259 instead of 257; this error has now been corrected. Additionally, the serine to tyrosine mutation shown at residue 320 was removed as this mutant was not included in the studies. This correction does not affect the results or conclusions of this work.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 168ef820-3116-5ec3-8c69-9e22c40e5f7d
DOI: 10.1074/jbc.aac118.002657

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.DOI 10.1074/jbc.aac118.002657Read

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathiesSemantic proximity Read

Tau proteinopathies and the prion concept.Semantic proximity Read

Tau Propagation, Different Tau Phenotypes, and Prion-like Properties of TauSemantic proximity Read

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different TauopathiesSemantic proximity Read

Distinct mechanistic pathways of early tauopathy revealed by <i>MAPT</i> mutationsSemantic proximity Read

Prions and Prion-like ProteinsSemantic proximity Read

Prion-like mechanisms in neurodegenerative diseasesSemantic proximity Read

Molecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation.Semantic proximity Read

Prion-like mechanisms and potential therapeutic targets in neurodegenerative disordersSemantic proximity Read

Prion-like disorders: blurring the divide between transmissibility and infectivitySemantic proximity Read

Distinct microscopic mechanisms for the accelerated aggregation of pathogenic Tau mutants revealed by kinetic analysis.Semantic proximity Read

Targeting prion-like protein spreading in neurodegenerative diseasesSemantic proximity Read