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Article

Epimorphin expression in intestinal myofibroblasts induces epithelial morphogenesis

2002-12-01

Abstract excerpt

The formation of the crypt-villus axis during gut ontogeny requires continued reciprocal interactions between the endoderm and mesenchyme. Epimorphin/syntaxin 2 (epimorphin) is a mesenchymal protein expressed in the fetal gastrointestinal tract during villus morphogenesis. To elucidate its role in gut ontogeny, the epimorphin cDNA was transfected, in sense and antisense orientations, into a rat intestinal myofibro...

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Identifiers and source

Literature Corpus work
16230183-79dd-56f3-ae21-3f2e47e33d4a
DOI
10.1172/jci0213588
Open publication

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