Article
Extracellular epimorphin modulates epidermal differentiation signals mediated by epidermal growth factor receptor.
Journal of dermatological science - 1 Mar 2013
Okugawa Yoji, Hirai Yohei
Abstract excerpt
BACKGROUND: The epidermal stratification/differentiation program is initiated in keratinocytes by a basement membrane-detachment cue and subsequently controlled by spatially and temporally regulated signaling molecules. The vital signals for the developmental behavior of the epidermis include those mediated by epidermal growth factor receptor (EGFR); however, regulatory elements responsible for activation have...
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