Article

Mutations in apicoplast rRNA genes are associated with clindamycin resistance and impair the ability of malaria parasites to infect mosquitoes

2026-04-08

Abstract excerpt

Drug resistance hampers malaria treatment and control. Resistance to nearly all clinically used antimalarials has emerged and spread globally. With multi-drug-resistant parasites now on the rise, understanding resistance mechanisms, and their ability to spread, is crucial for optimal treatment and control strategies. Clindamycin is an apicoplast-targeting antimalarial used as a partner compound in second-line trea...

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Literature Corpus work: 15ac1320-69bc-57e9-ae80-6b1ac461b8b3
DOI: 10.64898/2026.04.07.716898

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