Article

Integrated multi-omic analysis reveals novel subtype-specific regulatory interactions in pediatric B-cell acute lymphoblastic leukemia

2025-08-17

Abstract excerpt

Molecular subtyping of pediatric B-cell acute lymphoblastic leukemia (B-ALL) has improved patient outcomes through stratification and selection of targeted therapies. Despite extensive genomic and transcriptomic profiling of this cancer, few studies to date have characterized the proteomic landscape, although proteins are the direct targets of many therapeutic agents. In this study, we demonstrate the utility of m...

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Literature Corpus work: 1567517e-8aa9-52a8-963a-61f196913c1f
DOI: 10.1101/2025.08.13.670107

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