Article

Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1

2022-04-28

Abstract excerpt

Mutations in the viral genome of SARS-CoV-2 can impact the performance of molecular diagnostic assays. In some cases, such as S gene target failure, the impact can serve as a unique indicator of a particular SARS-CoV-2 variant and provide a method for rapid detection. Here we describe partial ORF1ab gene target failure (pOGTF) on the cobas ® SARS-CoV-2 assays, defined by a ≥2 thermocycles delay in detection of the...

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Literature Corpus work: 156409f4-fe74-5cd3-b1d1-10dcb317e7d2
DOI: 10.1101/2022.04.25.22274187

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