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Digital PCR Discriminates between SARS-CoV-2 Omicron Variants and Immune Escape Mutations.

Microbiology spectrum - 17 Aug 2023

Holland Steven C, Holland LaRinda A, Smith Matthew F, Lee Mihyun B, Hu James C, Lim Efrem S

Abstract excerpt

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, mutations arise that will allow the virus to evade immune defenses and therapeutics. Assays that can identify these mutations can be used to guide personalized patient treatment plans. Digital PCR (dPCR) is a fast and reliable complement to whole-genome sequencing that can be used to discriminate single nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37306573
DOI: 10.1128/spectrum.05258-22
PMCID: PMC10434287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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