CRISPR-based gene drives generate super-Mendelian inheritance in the disease vector Culex quinquefasciatus.

Abstract excerpt

<title>Abstract</title> <p><italic>Culex</italic> mosquitoes pose a significant public health threat as vectors for a variety of diseases including West Nile virus and lymphatic filariasis, and transmit pathogens threatening livestock, companion animals, and endangered birds. Rampant insecticide resistance makes controlling these mosquitoes challenging and necessitates the development of new control strategies. G...

Topics

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• Alleles
• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Gene Editing
• Genetics, Population
• Insect symbiosis and bacterial influences
• Models, Genetic
• Mosquito-borne diseases and control

Identifiers and source

Literature Corpus work

14f72a5f-25e6-5dd3-a422-c3d2f46ab3e9

DOI

10.21203/rs.3.rs-3054868/v1