Article

Rapid growth of acquired UBA1 mutations predisposes male patients to low-risk MDS

2024-05-23

Abstract excerpt

<title>Abstract</title> <p>VEXAS (vacuoles, E1-ubiquitin-like modifier activating enzyme, X-linked, autoinflammatory, somatic) syndrome is a recently described autoinflammatory disorder caused by acquired <italic>UBA1</italic> mutations in hematopoietic precursor cells. The prevalence, clinical significance, and genomic landscape of <italic>UBA1</italic>variants in patients with hematologic malignancies (HM) rema...

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Literature Corpus work: 14cb63a1-7061-56f9-bcb1-f4d6568013cd
DOI: 10.21203/rs.3.rs-4397067/v1

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