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The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy

2022-12-14

Abstract excerpt

Immunotherapy has revolutionised cancer treatment. However, not all cancer patients benefit, and current stratification strategies based primarily on PD1 status and mutation burden is far from perfect. We hypothesised that high activation of an innate response relative to the adaptive response may prevent proper tumour neoantigen identification and decrease the specific anticancer response, both in the presence an...

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Literature Corpus work
1462e6e2-c35f-555e-b917-7ffbe81b4449
DOI
10.1101/2022.12.13.520204
Open publication

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