Article

Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors

2024-05-17

Abstract excerpt

<h4>Background</h4> Medulloblastoma (MB) is the most malignant childhood brain cancer. Group 3 MB subtype accounts for about 25% of MB diagnoses and is associated with the most unfavorable outcomes. Herein, we report that more than half of group 3 MB tumors express melanoma antigens (MAGEs), which are potential prognostic and therapeutic markers. MAGEs are tumor antigens, expressed in several types of adult cance...

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Literature Corpus work: 14605feb-f2a5-5411-80af-07afca36f122
DOI: 10.1101/2024.05.14.594201

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