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Neoplastic and immune single cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma

2020-08-28

Abstract excerpt

Medulloblastoma (MB) is a heterogeneous disease in which neoplastic cells and associated immune cells contribute to disease progression. To better understand cellular heterogeneity in MB we use single-cell RNA sequencing, immunohistochemistry and deconvolution of transcriptomic data to profile neoplastic and immune populations in childhood MB samples. Neoplastic cells cluster primarily according to individual samp...

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Literature Corpus work
41a67cd9-a8c9-5d46-a286-1dc89efc3117
DOI
10.1101/2020.08.28.272021
Open publication

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Neoplastic and immune single cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastomaDOI 10.1101/2020.08.28.272021
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