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Article

Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy

31 Mar 2008

Abstract excerpt

OBJECT: Cancer testis antigens (CTAs) were initially identified by their ability to elicit autologous T-cell-mediated immune responses in patients with melanoma. The CTA genes are widely expressed in a variety of human cancers, such as melanoma, breast cancer, lung cancer, esophageal cancer, and hepatocellular carcinoma; however, their expression in pediatric brain tumors, such as medulloblastoma (MB), has not...

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PMID: 18377306
DOI: 10.3171/ped/2008/1/4/305

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