Article

Mitophagy mediates beige to white transition of human primary subcutaneous adipocytes <i>ex vivo</i>

2022-02-01

Abstract excerpt

Brown and beige adipocytes have multilocular lipid droplets, express uncoupling protein (UCP) 1, and promote energy expenditure. In rodents, when the stimulus of browning subsides, parkin-dependent mitophagy is activated and dormant beige adipocytes persist. In humans, however, the molecular events during beige to white transition were not studied in detail. In this study, human primary subcutaneous abdominal prea...

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Literature Corpus work: 14531cf0-4abd-5645-9dd6-679eaf4eb04c
DOI: 10.1101/2022.02.01.478645

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