Back to search

Article

Pan-cancer analysis and spatial validation in endometrial cancer reveal CD3D as a prognostic and immunological biomarker

2026-06-19

Abstract excerpt

<title>Abstract</title> <p>Background CD3D encodes the delta chain of the CD3 complex and is a core component of T-cell receptor (TCR) signaling, playing an essential role in T-cell activation and immune responses. While CD3D is well recognized as a T-cell-associated molecule, its expression patterns, prognostic relevance, and association with the tumor immune microenvironment across different cancer types have...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1445268d-944f-502c-b865-f9084464ad7a
DOI
10.21203/rs.3.rs-9719477/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pan-cancer analysis and spatial validation in endometrial cancer reveal CD3D as a prognostic and immunological biomarkerDOI 10.21203/rs.3.rs-9719477/v1
Prognostic and Immunological Characterization of NSD3 Evaluated Through an Integrative Pan-Cancer AnalysisSemantic proximity
Comprehensive analysis reveals a prognostic and therapeutic biomarker CD3D in the breast carcinoma microenvironmentSemantic proximity
High-plex spatial transcriptomic profiling reveals distinct immune components and the HLA class I/DNMT3A/CD8 modulatory axis in mismatch repair-deficient endometrial cancerSemantic proximity
Prognostic value and antitumor immune response elicited by FAT3 and LRP1B co-mutation in endometrial cancerSemantic proximity
Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.Semantic proximity
The landscape of tertiary lymphoid structures in endometrial cancer revealed through harmonized multi-level transcriptomicsSemantic proximity
Pan-cancer landscape of protein kinase D3: An integrative TCGA multi-omics analysis of clinical, molecular, and immunological roles.Semantic proximity
MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer typesSemantic proximity
Tumor immune microenvironment in endometrial cancer of different molecular subtypes: evidence from a retrospective observational study.Semantic proximity
Diagnostic, Prognostic, and Immunological Roles of CD177 in Cervical CancerSemantic proximity
The Spatial Immune Landscape of Mismatch Repair Deficient Endometrial Cancer: Implications for Clinical OutcomesSemantic proximity
Large-Scale Analysis and Clinical Samples Reveals the Specific Clinical and Immune Features of KDM4B in UCECSemantic proximity
Select a neighboring publication to make it the new centre.