Article
Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.
Gynecologic oncology - 1 Aug 2024
Jiang Zhansheng, Zhu Mingyu, Zhang Lu, Cui Haiyan, Jiang Richeng, Yang Yanfang
Abstract excerpt
OBJECTIVE: FAT3 and LRP1B are two tumor suppressor genes with high mutation frequency in multiple cancer types, we sought to investigate the prognostic and immunological significance of these two genes in EC. METHODS: Based on a cohort of 502 EC samples, we conducted a comprehensive analysis of its multidimensional data types including genomic, transcriptomic, and clinical information, the potential impact of...
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