Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-cancer landscape of protein kinase D3: An integrative TCGA multi-omics analysis of clinical, molecular, and immunological roles.

PloS one - 1 Jan 2026

Loaiza-Moss Jocshan, Leitges Michael

Abstract excerpt

Cancer remains a leading cause of mortality worldwide and a significant barrier to improving quality of life across all populations. The protein kinase D family, including PRKD3, has been demonstrated to play a crucial role in cancer development through its involvement in regulating key cellular processes. Although growing evidence highlights the role of PRKD3 in the tumorigenesis of certain cancers, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA Copy Number Variations
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Multiomics

Share to Neoplasms

Share to Prognosis

Share to Protein Kinase C

Source

Open in PubMed Open full text

Identifiers

PMID: 41931575
DOI: 10.1371/journal.pone.0346173
PMCID: PMC13048501

Genes

PRKD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer landscape of protein kinase D3: An integrative TCGA multi-omics analysis of clinical, molecular, and immunological roles.PMID 41931575Read ↗

MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer typesSemantic proximity Read ↗

Prognostic and Immunological Characterization of NSD3 Evaluated Through an Integrative Pan-Cancer AnalysisSemantic proximity Read ↗

CDKN3 alterations in the Kidney renal clear cell carcinoma: prognosis and immunotherapy efficacySemantic proximity Read ↗

Pan-cancer analysis of PDZK1IP1 reveals its role in tumorigenesis and tumor immunity: focused validation in thyroid carcinoma.Semantic proximity Read ↗

Potential Value of PRKDC as a Therapeutic Target and Prognostic Biomarker in Pan-CancerSemantic proximity Read ↗

Human pan-cancer analysis of the predictive biomarker for the CDKN3Semantic proximity Read ↗

Pan-Cancer Analysis of Histone Methyltransferase KMT2D with Potential Implications for Prognosis and Immunotherapy in Human CancerSemantic proximity Read ↗

Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors.Semantic proximity Read ↗

Human pan-cancer analysis of the predictive biomarker for the CDKN3Semantic proximity Read ↗

Integrated spatial and single cell transcriptomics identifies PRKDC as a dual prognostic biomarker and therapeutic target in hepatocellular carcinomaSemantic proximity Read ↗

NDC80 status pinpoints mitotic kinase inhibitors as emerging therapeutic options in clear cell renal cell carcinomaSemantic proximity Read ↗

Pan-Cancer Genetic Profiles of Mitotic DNA Integrity Checkpoint Protein KinasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.