Article

DNA repair and response to therapy : exploring their relation in epithelial ovarian cancer models

2021-01-01

Abstract excerpt

Epithelial ovarian cancer (EOC) is often characterized by defects in DNA repair pathways, which partially explain its sensitivity to platinum compounds and to poly (ADP-ribose) polymerase inhibitors (PARPi). However, EOC almost invariably relapses with a drug resistant, incurable disease. Biomarkers able to predict the response to therapy could ameliorate the management of EOC patients. The studies herein reported...

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Literature Corpus work: 141fb253-d730-562e-9883-ef2c6b36975a
DOI: 10.21954/ou.ro.0001278a

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