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Integrating Bulk and Single-cell RNA-seq to Construct a Macrophage-related Prognostic Model for Prognostic Stratification in Triple-negative Breast Cancer

1 Jan 2024

Abstract excerpt

Background: Triple-negative breast cancer (TNBC) is a poor prognostic subtype of breast cancer due to limited treatment.Macrophage plays a critical role in tumor growth and survival.Our study intends to explore the heterogeneity of macrophage in TNBC and establish a macrophage-related prognostic model for TNBC prognostic stratification.Materials and Methods: Seurat package was conducted to analyze the single-cell...

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PMID: 39440065
DOI: 10.7150/jca.101042

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