Article

Rare Maternally Inherited Coding Variants on Chromosome X Carry Predominantly Male Risk in Autism, Tourette Syndrome, and Attention-deficit/Hyperactivity Disorder

2022-09-23

Abstract excerpt

<h4>ABSTRACT</h4> Autism spectrum disorders (ASD), Tourette syndrome (TS), and attention-deficit/hyperactivity disorder (ADHD) display strong male sex bias, due to a combination of genetic and biological factors, as well as selective ascertainment. While the hemizygous nature of chromosome X (Chr X) in males has long been postulated as a key point of “male vulnerability”, rare genetic variation on this chromosome...

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Literature Corpus work: 13bfc334-7597-5056-baa9-2cfed671f45f
DOI: 10.1101/2022.09.22.22280248

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