Article

T cell gene therapy in vascular pathology

2012-01-01

Abstract excerpt

The immune system is a key contributor to atherosclerosis-related cardiovascular diseases (CVD) however, at present there are no targeted therapies specific for the inflamed vessel wall. Multiple leukocyte subsets have been shown to play a significant role in CVD and among them, CD4 T cells are receiving growing interest. Here we investigated whether T cells could be utilised as delivery vehicles in experimental a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1371d043-7596-5312-b3dd-712e8b81f489
DOI: 10.48730/tvcp-b549

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

T cell gene therapy in vascular pathologyDOI 10.48730/tvcp-b549Read

Emergence of targeted molecular imaging in atherosclerotic cardiovascular disease.Semantic proximity Read

Approaches and Recent Trends in Gene Delivery for Treatment of Atherosclerosis.Semantic proximity Read

Ultrasound Molecular Imaging of Atherosclerosis Using Small-Peptide Targeting Ligands Against Endothelial Markers of Inflammation and Oxidative StressSemantic proximity Read

Ultrasound-guided left heart injection: a safer and more efficient strategy for mouse thoracic aortic gene deliverySemantic proximity Read

Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties.Semantic proximity Read

Flow Cytometric Analysis of Immune Cells Within Murine Aorta.Semantic proximity Read

Cytomegalovirus infection accelerates inflammation in vascular tissue overexpressing monocyte chemoattractant protein-1.Semantic proximity Read

Vaccination against TIE2 reduces atherosclerosis.Semantic proximity Read

Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes.Semantic proximity Read

Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-pSemantic proximity Read

Noninvasive ultrasound molecular imaging of the effect of statins on endothelial inflammatory phenotype in early atherosclerosis.Semantic proximity Read

Homing markers for atherosclerosis: applications for drug delivery, gene delivery and vascular imagingSemantic proximity Read