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Article

Vaccination against TIE2 reduces atherosclerosis.

Atherosclerosis - 1 Jun 2009

Hauer Arnaud D, Habets Kim L L, van Wanrooij Eva J A, de Vos Paula, Krueger Joerg, Reisfeld Ralph A, van Berkel Theo J C, Kuiper Johan

Abstract excerpt

BACKGROUND: TIE2(+) cells play a crucial role in processes that are involved in atherosclerosis, such as angiogenesis. Therefore, the specific deletion of TIE2(+) cells by means of DNA vaccination may affect atherosclerosis. METHODS: Cellular immunity against cells that overexpress TIE2 was established in LDLr(-/-) mice by a novel oral DNA vaccination technique, in which an attenuated Salmonella typhimurium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19022447
DOI: 10.1016/j.atherosclerosis.2008.09.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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