Pathogenic <i>Bacteroides fragilis</i> strains can emerge from gut-resident commensals

Abstract excerpt

<h4>SUMMARY</h4> Bacteroides fragilis is a prominent member of the human gut microbiota, playing crucial roles in maintaining gut homeostasis and host health. Although it primarily functions as a beneficial commensal, B. fragilis can become pathogenic. To determine the genetic basis of its duality, we conducted a comparative genomic analysis of 813 B. fragilis strains, representing both commensal and pathogenic...

Topics

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• Bacterial Identification and Susceptibility Testing
• Bacteroides fragilis
• Drug Resistance, Bacterial
• Gastrointestinal Microbiome
• Genetic Variation
• Genome, Bacterial
• Phylogeny
• Whole Genome Sequencing

Identifiers and source

Literature Corpus work

1358f354-63ca-5469-831d-676f0e64118a

DOI

10.1101/2024.06.19.599758