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Comparative Evolutionary Genomics Reveals Genetic Diversity and Differentiation in Bacteroides fragilis.

Genes - 27 Nov 2024

Muto Yoshinori, Tanaka Kaori

Abstract excerpt

BACKGROUND/OBJECTIVES: Bacteroides fragilis is the pathogenic anaerobe most commonly isolated from intra-abdominal infections, abscesses, and blood. Despite its clinical importance, research on its pan-genome-scale evolution is still limited. METHODS: Herein, we analyzed the pan-genome architecture of 374 B. fragilis strains to explore their intra-species genomic diversity and evolutionary patterns. RESULTS: Our...

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PMID: 39766787
DOI: 10.3390/genes15121519

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