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Article

BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis

2025-04-22

Abstract excerpt

Ageing is characterised by persistent low-grade inflammation that is linked to impaired tissue homeostasis and functionality. However, the molecular mechanisms driving age-associated inflammation remain poorly understood. The mammalian skin is a clinically relevant target of age-driven inflammation associated with compromised barrier function, inefficient wound healing, elevated oxidative stress, and DNA damage ac...

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Identifiers and source

Literature Corpus work
1346ac4b-73b3-51d8-b1d6-5c5632525b9c
DOI
10.1101/2025.04.22.649967
Open publication

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BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermisDOI 10.1101/2025.04.22.649967
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