Article
Conservation of gene essentiality in Apicomplexa and its application for prioritization of anti-malarial drug targets
2017-01-09
Abstract excerpt
New anti-malarial drugs are needed to address the challenge of artemisinin resistance and to achieve malaria elimination and eradication. Target-based screening of inhibitors is a major approach for drug discovery, but its application to malaria has been limited by the availability of few validated drug targets in Plasmodium . Here we utilize the recently available large-scale gene essentiality data in Plasmodiu...
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Identifiers and source
- Literature Corpus work
- 12ef0d69-af78-5c28-b975-75c15475c909
- DOI
- 10.12688/f1000research.10559.1