Article

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

2024-11-26

Abstract excerpt

<title>Abstract</title> <p>The identification of novel drug targets for the purpose of designing small molecule inhibitors is key component to modern drug discovery. In malaria parasites, discoveries of antimalarial targets have primarily occurred retroactively by investigating the mode of action of compounds found through phenotypic screens. Although this method has yielded many promising candidates, it is time-...

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Literature Corpus work: 3729fb70-e4ba-59f3-b19b-a288e9e8f7c6
DOI: 10.21203/rs.3.rs-5412515/v1

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