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The Amplified Burden of Depression in Drug-Resistant Epilepsy: Role of Limbic Network Dynamic Reconfiguration

2025-07-22

Abstract excerpt

<h4>Objectives: </h4> To explore potential associations between drug resistance and limbic network (LN) dynamic functional interactions in temporal lobe epilepsy (TLE), whether these LN alterations are associated with and potentially mediate comorbid depression severity, and their potential neurochemical and transcriptomic underpinnings. <h4>Methods:</h4> This cross-sectional study included 49 patients in the Resp...

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Literature Corpus work
12d39c1f-09b7-522b-aa3c-57c0018ef79a
DOI
10.1101/2025.07.20.665759
Open publication

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The Amplified Burden of Depression in Drug-Resistant Epilepsy: Role of Limbic Network Dynamic ReconfigurationDOI 10.1101/2025.07.20.665759
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