Article

A Modeling Framework for Exploring Sampling and Observation Process Biases in Genome and Phenome-wide Association Studies using Electronic Health Records

2018-12-21

Abstract excerpt

Large-scale agnostic association analyses based on existing observational health care databases such as electronic health records have been a topic of increasing interest in the scientific community. However, particular challenges of non-probability sampling and phenotype misclassification associated with the use of these data sources are often ignored in standard analyses. In general, the extent of the bias that...

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Literature Corpus work: 1292932a-12a3-56c6-b07e-c13bf3ab6613
DOI: 10.1101/499392

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