Article

Privacy-Enhancing Sequential Learning under Heterogeneous Selection Bias in Multi-Site EHR Data

2025-09-28

Abstract excerpt

<h4>Objective</h4> To develop privacy-enhancing statistical methods for estimation of binary disease risk model association parameters across multiple electronic health record (EHR) sites with heterogeneous selection mechanisms, without sharing raw individual-level data. We illustrate their utility through a cross-biobank analysis of smoking and 97 cancer subtypes using data from the NIH All of Us (AOU) and the M...

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Literature Corpus work: 0b310d0b-b9e6-5fac-b1ee-b8a6789c9e8a
DOI: 10.1101/2025.09.26.25336642

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