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Article

Reducing Bias Due to Outcome Misclassification for Epidemiologic Studies Using EHR-derived Probabilistic Phenotypes.

Epidemiology (Cambridge, Mass.) - 1 Jul 2020

Hubbard Rebecca A, Tong Jiayi, Duan Rui, Chen Yong

Abstract excerpt

Epidemiologic studies using electronic health record (EHR)-derived phenotypes as outcomes are subject to bias due to phenotyping error. In the case of dichotomous phenotypes, existing methods for misclassified outcomes can be used to reduce bias. In this article, we present a bias correction approach for EHR-derived probabilistic phenotypes: continuous predicted probabilities of the outcome of interest. This...

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Identifiers

PMID: 32282406
DOI: 10.1097/EDE.0000000000001193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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