Article

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches

2020-07-26

Abstract excerpt

In order to elucidate novel aspects of the host response to SARS-CoV-2 we performed RNA sequencing on peripheral blood samples across 77 timepoints from 46 subjects with COVID-19 and compared them to subjects with seasonal coronavirus, influenza, bacterial pneumonia, and healthy controls. Early SARS-CoV-2 infection triggers a conserved transcriptomic response in peripheral blood that is heavily interferon-driven b...

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Literature Corpus work: 11ffb3b3-fc10-5eaa-8a56-c7dde0592a61
DOI: 10.1101/2020.07.20.20155507

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