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Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype.

Clinical pharmacology and therapeutics - 1 May 2023

Gammal Roseann S, Pirmohamed Munir, Somogyi Andrew A, Morris Sarah A, Formea Christine M, Elchynski Amanda L, Oshikoya Kazeem A, McLeod Howard L, Haidar Cyrine E, Whirl-Carrillo Michelle, Klein Teri E, Caudle Kelly E, Relling Mary V

Abstract excerpt

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with development of acute hemolytic anemia in the setting of oxidative stress, which can be caused by medication exposure. Regulatory agencies worldwide warn against the use of certain medications in persons with G6PD deficiency, but in many cases, this information is conflicting, and the clinical evidence is sparse. This guideline provides...

Topics

Humans
Glucosephosphate Dehydrogenase
Glucosephosphate Dehydrogenase Deficiency
Pharmacogenetics
Hemolysis
Genotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36049896
DOI: 10.1002/cpt.2735
PMCID: PMC10281211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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