Article

NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

2021-03-30

Abstract excerpt

<h4>SUMMARY</h4> The heterogeneous complexes comprising the family of Polycomb Repressive Complex 1 (PRC1) are instrumental to establishing facultative heterochromatin that is repressive to transcription. Yet, two PRC1 species, PRC1.3 and PRC1.5, are known to comprise novel components, AUTS2, P300, and CK2 that convert this repressive function to that of transcription activation. Here, we report that patients har...

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Literature Corpus work: 11a94a16-d50d-525e-afc4-7fcb1f72fad2
DOI: 10.1101/2021.03.30.437620

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