Article

The influence of human genetic variation on early transcriptional responses and protective immunity following immunization with Rotarix vaccine in infants in Ho Chi Minh City in Vietnam: A study protocol for an open single-arm interventional trial

2020-10-19

Abstract excerpt

<h4>Background: </h4> : Rotavirus (RoV) remains the leading cause of acute gastroenteritis in infants and children aged under five years in both high- and low-middle-income countries (LMICs). In LMICs, RoV infections are associated with substantial mortality. Two RoV vaccines (Rotarix and Rotateq) are widely available for use in infants, both of which have been shown to be highly efficacious in Europe and North Am...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 11a89d6e-e867-5e2e-b36f-6019c6af8f0d
DOI: 10.12688/wellcomeopenres.16090.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The influence of human genetic variation on early transcriptional responses and protective immunity following immunization with Rotarix vaccine in infants in Ho Chi Minh City in Vietnam: A study protocol for an open single-arm interventional trialDOI 10.12688/wellcomeopenres.16090.1Read

Rotavirus genotype trends from 2013 to 2018 and vaccine effectiveness in southern Vietnam.Semantic proximity Read

Host genetic determinants of rotavirus disease and immunity in African childrenSemantic proximity Read

Genomic insights into mRNA COVID-19 vaccines efficacy: Linking genetic polymorphisms to waning immunity.Semantic proximity Read

Integrative genomic analysis of the human immune response to influenza vaccination.Semantic proximity Read

Molecular epidemiology of noroviruses detected in Vietnamese children with acute gastroenteritis from 2012 to 2015.Semantic proximity Read

Effectiveness of Monovalent Rotavirus Vaccine Among Young Children in Pakistan: a Test-Negative Case-Control EvaluationSemantic proximity Read

[Rotavirus genomics. Public health impact].Semantic proximity Read

Vaccinomics: current findings, challenges and novel approaches for vaccine development.Semantic proximity Read

Personalized Health and the Coronavirus Vaccines --Do Individual Genetics Matter?Semantic proximity Read

TLR genetic variation is associated with Rotavirus-specific IgA seroconversion in South African Black infants after two doses of Rotarix vaccine.Semantic proximity Read

Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial.Semantic proximity Read

The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take.Semantic proximity Read