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Article

Integrative genomic analysis of the human immune response to influenza vaccination.

eLife - 16 Jul 2013

Franco Luis M, Bucasas Kristine L, Wells Janet M, Niño Diane, Wang Xueqing, Zapata Gladys E, Arden Nancy, Renwick Alexander, Yu Peng, Quarles John M, Bray Molly S, Couch Robert B, Belmont John W, Shaw Chad A

Abstract excerpt

Identification of the host genetic factors that contribute to variation in vaccine responsiveness may uncover important mechanisms affecting vaccine efficacy. We carried out an integrative, longitudinal study combining genetic, transcriptional, and immunologic data in humans given seasonal influenza vaccine. We identified 20 genes exhibiting a transcriptional response to vaccination, significant genotype effects...

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Share to Influenza A Virus, H1N1 Subtype
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Humoral

Share to Influenza A Virus, H3N2 Subtype

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Source

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Identifiers

PMID: 23878721
DOI: 10.7554/eLife.00299
PMCID: PMC3713456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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