Article

Epigenetic dynamics of centromeres and neocentromeres in <i>Cryptococcus deuterogattii</i>

2020-11-06

Abstract excerpt

Deletion of native centromeres in the human fungal pathogen Cryptococcus deuterogattii leads to neocentromere formation. Native centromeres span truncated transposable elements, while neocentromeres do not and instead span actively expressed genes. To explore the epigenetic organization of neocentromeres, we analyzed the distribution of the heterochromatic histone modification H3K9me2, 5mC DNA methylation and the...

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Literature Corpus work: 117544f1-b1cb-5029-9a64-0804f8365704
DOI: 10.1101/2020.11.05.369892

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