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Pediatric Low-grade Glioma with FGFR1:TACC1 Fusion Mutation Displays Aggressive Tumor Biology: A Case Report and Literature Review

2025-01-07

Abstract excerpt

Abstract Background Pediatric low-grade gliomas (pLGG) are the most common childhood solid tumors. While typically indolent with excellent prognoses, certain mutations have been associated with aggressive tumor behavior. Case Presentation A 19-month-old with biopsy-confirmed pLGG experienced symptoms and progression of residual tumor two months following debulking surgery. Repeat debulking and biopsies similarly c...

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Literature Corpus work
1174a184-9f72-598a-8afc-f792bb54e120
DOI
10.22541/au.173623241.19851384/v1
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Pediatric Low-grade Glioma with FGFR1:TACC1 Fusion Mutation Displays Aggressive Tumor Biology: A Case Report and Literature ReviewDOI 10.22541/au.173623241.19851384/v1
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