Article
How Do Uterine Natural Killer and Innate Lymphoid Cells Contribute to Successful Pregnancy?
Frontiers in immunology - 1 Jan 2021
Huhn Oisín, Zhao Xiaohui, Esposito Laura, Moffett Ashley, Colucci Francesco, Sharkey Andrew M
Abstract excerpt
Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both before and during pregnancy. Circumstantial evidence suggests they play important roles in regulating placental development but exactly how they contribute to the successful outcome of pregnancy is still unclear. Uterine ILCs (uILCs) include subsets of tissue-resident natural killer (NK) cells and ILCs, and until recently...
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