Article

The Evolution of Placental Invasion and Cancer Metastasis are Causally Linked

2019-01-23

Abstract excerpt

Among mammals, the extent of placental invasion is correlated with vulnerability to malignancy. Animals with more invasive placentation (e.g. humans) are more vulnerable to malignancy, whereas animals with a non-invasive placenta (e.g. ruminants) are less likely to develop malignant cancer. To explain this correlation, we propose the hypothesis of Evolved Levels of Invasibility (ELI) positing that the permissiven...

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Literature Corpus work: 114cbdfe-f04e-5ee8-8e0d-54cf92e01af2
DOI: 10.1101/528646

Open publication

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