Malignant cancer and invasive placentation: A case for positive pleiotropy between endometrial and malignancy phenotypes

Abstract excerpt

Cancer metastasis is an invasive process that involves the transplantation of cells into new environments. Since human placentation is also invasive, hypotheses about a relationship between invasive placentation in eutherian mammals and metastasis have been proposed. The relationship between metastatic cancer and invasive placentation is usually presented in terms of antagonistic pleiotropy. According to this...

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