Article

GRAFIMO: variant and haplotype aware motif scanning on pangenome graphs

2021-02-05

Abstract excerpt

Transcription factors (TFs) are proteins that promote or reduce the expression of genes by binding short genomic DNA sequences known as transcription factor binding sites (TFBS). While several tools have been developed to scan for potential occurrences of TFBS in linear DNA sequences or reference genomes, no tool exists to find them in pangenome variation graphs (VGs). VGs are sequence-labelled graphs that can eff...

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Literature Corpus work: 113cf4bc-706c-564f-80fa-2d748df125e9
DOI: 10.1101/2021.02.04.429752

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