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Article

GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs.

PLoS computational biology - 1 Sept 2021

Tognon Manuel, Bonnici Vincenzo, Garrison Erik, Giugno Rosalba, Pinello Luca

Abstract excerpt

Transcription factors (TFs) are proteins that promote or reduce the expression of genes by binding short genomic DNA sequences known as transcription factor binding sites (TFBS). While several tools have been developed to scan for potential occurrences of TFBS in linear DNA sequences or reference genomes, no tool exists to find them in pangenome variation graphs (VGs). VGs are sequence-labelled graphs that can...

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PMID: 34570769
DOI: 10.1371/journal.pcbi.1009444
PMCID: PMC8519448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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